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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0128L | Vigabatrin Hydrochloride | γ-Vinyl-GABA hydrochloride | GABA Receptor |
Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), which irreversibly inhibits the catabolism of GABA by GABA transaminase. | |||
T40659L | γ-Acetylenic GABA hydrochloride | γ-Acetylenic GABA hydrochloride(57659-38-8 Free base) | Transaminase , GABA Receptor |
γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor. | |||
T77795 | L-DABA hydrobromide | L-2,4-Diaminobutyric acid hydrobromide | Others , Endogenous Metabolite |
L-DABA hydrobromide (L-2,4-Diaminobutyric acid hydrobromide) is a potent GABA transaminase inhibitor with antitumor and anticonvulsant activity for the study of neurological disorders. | |||
T6474 | Divalproex Sodium | Valproate semisodium,Epival | HDAC |
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme... | |||
T7622L | Gabazine free base | Chebi:34968,SR95531,C13796,J331.170H,SR 95531 | |
Gabazine free base is a specific antagonist of the GABA receptor. It does not affect GABA-transaminase or glutamate-decarboxylase activities. | |||
T24080 | Gabaculine HCl | 708-B,Gabaculine hydrochlorlide | |
Gabaculine is an irreversible inhibitor of GABA transaminase (GABA-T; Ki: 2.9 μM). Gabaculine alters plastid development and differentially affects the abundance of plastid-encoded DPOR and nuclear-encoded GluTR. | |||
T40659 | γ-Acetylenic GABA | 4-Aminohex-5-ynoic acid,γ-Acetylenic GABA | |
γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase. This compound effectively raises the concentration of γ-Aminobutyric acid (GABA) in the brain of rats. | |||
T62185 | GABA-AT-IN-1 | ||
GABA-AT-IN-1 (Compound 6) is an inhibitor of γ-aminobutyric acid transaminase (GABA-AT) that crosses the blood-brain barrier. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7595 | L-DABA | L-2,4-Diaminobutyric acid,L-DAB HBR | GABA Receptor , Endogenous Metabolite |
L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM). | |||
T2S1814 | P-Hydroxybenzaldehyde | 4-Formylphenol,4-hydroxybenzaldehyde,p-Oxybenzaldehyde | Transaminase , GABA Receptor , Endogenous Metabolite |
1. p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory activity was higher than that of valproic... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00857 | ABAT Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine. ABAT Protein, Hu... |